Senior Scientist, Process Development - Bioconjugation

Dyne Therapeutics

Waltham, MA, United States
$147,000—$180,000 usd py
**
Bioconjugation process development
Oligonucleotide conjugate manufacturing
Cdmo management
** Dyne Therapeutics is seeking a Senior Scientist in Process Development focused on bioconjugation to ensure the development of robust GMP manufacturing processes for antibody oligonucleotide conjugates. The role requires extensive experience in bioconjugates and oversight of external CDMO activities, along with strong collaboration across various internal and external stakeholders. **

Job Summary

  • Responsible for process development, technology transfer, and management of external CDMO activities to ensure development of robust and reliable GMP manufacturing processes for antibody oligonucleotide conjugates and intermediates.
  • Lead internal CMC Process Development activities via hands-on contribution in the laboratory and manage external process development, optimization, and tech transfer of new programs.
  • Represent bioconjugation Drug Substance process as a technical leader in internal cross-functional CMC teams and prepare technical source documents for global regulatory submission.

Matching Summary

Match Score: 75

** Dyne Therapeutics is seeking a Senior Scientist in Process Development focused on bioconjugation to ensure the development of robust GMP manufacturing processes for antibody oligonucleotide conjugates. The role requires extensive experience in bioconjugates and oversight of external CDMO activities, along with strong collaboration across various internal and external stakeholders. **

Salary

$147,000—$180,000 USD

Skills & Requirements

Must-have

  • bioconjugation process development
  • oligonucleotide conjugate manufacturing
  • CDMO management
  • GMP production
  • CMC strategy

Nice-to-have

  • morpholino oligonucleotides
  • antisense oligonucleotides
  • siRNA familiarity
  • emerging technology implementation

Key Requirements

  • PhD or equivalent experience
  • 5+ years related experience
  • Biopharmaceutical CMC management experience
  • Hands-on analytical techniques experience
  • Oversight of external CDMO experience

Work Rights

Not specified

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