Associate Principal Scientist – Analytical Project Lead

AstraZeneca

Macclesfield, UK
Competitive salary; flexible employee benefits fun...
Hybrid
Hplc/uplc and lc-ms chromatographic techniques
Analytical control strategy definition and leadership
Cmc content authoring for regulatory submissions
This role involves leading analytical strategy and delivery for oral solid dosage forms and parenteral products from early development through commercialization

Job Summary

  • This role involves leading analytical strategy and delivery for oral solid dosage forms and parenteral products from early development through commercialization.
  • The successful candidate will partner across formulation, engineering, manufacturing, QA, and Regulatory to deliver robust methods and efficient control strategies.
  • AstraZeneca offers a competitive salary, flexible employee benefits fund, pension contributions, and a performance recognition scheme.

Matching Summary

This role involves leading analytical strategy and delivery for oral solid dosage forms and parenteral products from early development through commercialization.

Salary

Competitive salary; Flexible employee benefits fund including holiday purchase and pension contributions; Share Save Plans and performance recognition scheme

Skills & Requirements

Must-have

  • HPLC/UPLC and LC-MS chromatographic techniques
  • Analytical control strategy definition and leadership
  • CMC content authoring for regulatory submissions
  • Method validation and transfer execution
  • Stability indicating method development
  • Root cause analysis and data integrity assessments

Nice-to-have

  • Multivariate experimental design and DoE concepts
  • Python or R scripting for data wrangling
  • Bayesian optimization for robustness tuning
  • Chemometrics for pattern recognition
  • Mentoring and coaching scientific teams
  • Experience with peptides and oligonucleotides

Key Requirements

  • MSc or PhD in Analytical Chemistry or related field
  • Significant experience in pharmaceutical analytical science
  • Proven record of leading global scientific projects
  • Strong proficiency in chromatographic techniques
  • Knowledge of regulatory CMC requirements

Work Rights

Not specified

Tailored Resume

Cover Letter