The Vaccines and Advanced Biotechnologies (VAX) Process R&D team develops and manufactures Drug Substance and Drug Product Intermediates for the company's pipeline, from preclinical to commercialization
Job Summary
The Vaccines and Advanced Biotechnologies (VAX) Process R&D team develops and manufactures Drug Substance and Drug Product Intermediates for the company's pipeline, from preclinical to commercialization.
The Associate Principal Scientist will lead downstream process development for vaccine products, de-risk later stage development, and represent the functional area in cross-functional teams.
The role offers a comprehensive benefits package including medical, dental, vision, retirement benefits, paid holidays, vacation, and sick days.
Matching Summary
The Vaccines and Advanced Biotechnologies (VAX) Process R&D team develops and manufactures Drug Substance and Drug Product Intermediates for the company's pipeline, from preclinical to commercialization.
Salary
Base: $139,600.00 - $219,700.00; Bonus/Equity: Eligible for annual bonus and long-term incentive; Benefits: Comprehensive package including medical, dental, vision, 401(k), paid holidays, vacation, and sick days
Skills & Requirements
Must-have
Downstream process design and development
Recombinant protein purification
Column chromatography and filtration
Biomolecule conjugation techniques
cGMP manufacturing understanding
Statistical design of experiments (DOE)
Nice-to-have
Mentoring junior staff
Authoring CMC regulatory documentation
Process and technology transfer
AKTA platform experience
Flexibility in responding to changing priorities
Key Requirements
BS/MS/PhD with 7/5/3 years of experience
At least 5 years hands-on downstream process optimization
Strong understanding of large molecule purification unit operations
Experience with statistical design of experiments (DOE)