Principal Scientist, Cardiovascular Translational Biomarker

Bristol Myers Squibb

Princeton, NJ, US
Base: $135,800 - $164,563; bonus/equity: + incenti...
50% onsite
Cardiovascular biology background
In vivo functional-structural analyses
Cell culture of primary cardiac cells
Bristol Myers Squibb is seeking a Principal Scientist specializing in cardiovascular translational biomarkers to support the progression of late-discovery programs to clinical trials. The ideal candidate will possess a strong background in cardiovascular biology and significant lab experience, particularly in defining pharmacodynamic biomarkers

Job Summary

  • This role involves collaborating with the development organization to drive the progression of cardiovascular programs from discovery to early phase clinical trials.
  • The position requires establishing pharmacodynamic endpoints consistent with mechanism of action using in vivo, ex vivo, or in vitro assays.
  • Bristol Myers Squibb offers a wide variety of competitive benefits including health coverage, financial well-being protection, and flexible time off.

Matching Summary

Match Score: 85

Bristol Myers Squibb is seeking a Principal Scientist specializing in cardiovascular translational biomarkers to support the progression of late-discovery programs to clinical trials. The ideal candidate will possess a strong background in cardiovascular biology and significant lab experience, particularly in defining pharmacodynamic biomarkers.

Salary

Base: $135,800 - $164,563; Bonus/Equity: Additional incentive cash and stock opportunities available; Benefits: Health, dental, vision, 401(k), paid time off, and wellbeing support

Skills & Requirements

Must-have

  • Cardiovascular biology background
  • In vivo functional-structural analyses
  • Cell culture of primary cardiac cells
  • iPSC-CM and engineered heart tissues
  • Rodent handling expertise
  • Imaging biomarker knowledge (MRI, PET, Ultrasound)
  • Hands-on immunoassay and qPCR skills

Nice-to-have

  • Self-motivated and detail-oriented
  • Collaborative matrixed team environment
  • Experience managing external CROs
  • Strong experimental design capabilities
  • Ability to articulate 3Rs principles

Key Requirements

  • Ph.D. in Life Sciences with 4+ years experience
  • Master's Degree with 6+ years industry experience
  • Bachelor's Degree with 8+ years academic/industry experience
  • 2+ years relevant industry experience post-terminal degree preferred
  • Expertise in iPSC-CM and primary cardiac cell culturing

Work Rights

Not specified

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