Principal Scientist – Bioseparation & Analytical Development
Business Elements
Ann Arbor, MI, US
Onsite
Phd in analytical chemistry or related field
8-15 years biopharmaceutical analytical experience
Expertise in hplc, uplc, sec, iex chromatography
Element is seeking a Principal Scientist in Bioseparation & Analytical Development to lead the advancement of analytical methods for large molecule therapeutics. This role requires significant hands-on experience and expertise in bioseparation sciences, with a focus on various biologic modalities
Job Summary
This role involves leading the development and validation of advanced analytical methods for a broad range of complex biologics modalities.
The successful candidate will apply deep expertise in chromatography and mass spectrometry to support discovery through late-stage CMC activities.
Element is a global testing and certification business seeking a leader to drive innovation in analytical science within an onsite laboratory environment.
Matching Summary
Match Score: 85
Element is seeking a Principal Scientist in Bioseparation & Analytical Development to lead the advancement of analytical methods for large molecule therapeutics. This role requires significant hands-on experience and expertise in bioseparation sciences, with a focus on various biologic modalities.
Skills & Requirements
Must-have
PhD in Analytical Chemistry or related field
8-15 years biopharmaceutical analytical experience
Expertise in HPLC, UPLC, SEC, IEX chromatography
Proficiency in LC-MS/MS and high-resolution mass spectrometry
Hands-on CE-SDS and cIEF capillary electrophoresis skills
Experience with GMP compliance and regulatory submissions
Nice-to-have
Experience with MAM workflows and automation
Background in glycan mapping and PTM quantification
Knowledge of emerging biologics like mRNA and viral vectors
Strong scientific writing for regulatory documentation
Client-facing CRO project execution experience
Key Requirements
PhD required or MS with extensive industry experience
8-15+ years in biopharmaceutical analytical development