Senior Scientist,oligo Chemistry

Brii Biosciences

Shanghai, China
On-site
Expertise in oligonucleotide synthesis
Solid phase chemistry knowledge
Post-synthetic ligation approaches
Brii Biosciences is seeking a Senior Scientist specializing in oligonucleotide chemistry for their drug discovery team in Shanghai. The ideal candidate will have expertise in the design, synthesis, and purification of oligonucleotide constructs, along with experience in analytical methods and a strong background in scientific research

Job Summary

  • The role involves designing, synthesizing, and purifying novel oligonucleotide constructs including siRNA and ASO modalities.
  • Candidates must independently plan and execute in vivo studies to analyze pharmacological and toxicology results.
  • The position requires strict adherence to high data integrity standards using an integrated electronic laboratory notebook system.

Matching Summary

Match Score: 85

Brii Biosciences is seeking a Senior Scientist specializing in oligonucleotide chemistry for their drug discovery team in Shanghai. The ideal candidate will have expertise in the design, synthesis, and purification of oligonucleotide constructs, along with experience in analytical methods and a strong background in scientific research.

Skills & Requirements

Must-have

  • Expertise in oligonucleotide synthesis
  • Solid phase chemistry knowledge
  • Post-synthetic ligation approaches
  • siRNA and antisense oligonucleotide design
  • Chromatographic purification proficiency
  • Analytical method development skills
  • State-of-the-art synthesizer operation

Nice-to-have

  • Experience with novel RNA monomers
  • In vivo study design capabilities
  • Cross-functional team collaboration
  • Creative problem-solving abilities
  • Strong scientific presentation skills
  • Electronic lab notebook (ELN) experience
  • CRO team management experience

Key Requirements

  • Master's degree in Chemistry or Bachelor's with 3+ years experience
  • 1+ year of industry experience in oligonucleotide synthesis preferred
  • Proven track record in chromatographic purification and characterization

Work Rights

Not specified

Tailored Resume

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