Senior Scientist Ii-cell, Process Development

AstraZeneca

Ucar-t platform development
Process parameter optimization
Pat and statistical modeling
Develop UCAR-T platform across key unit operations and build up representative small-scale model

Job Summary

  • Develop UCAR-T platform across key unit operations and build up representative small-scale model.
  • Optimize process parameters and materials to improve process performance and product quality, ensuring lot-to-lot consistency.
  • Translate lab processes to clinical-grade closed and automated systems and support INDa filing readiness, late-stage characterization and PPQ execution.

Matching Summary

Develop UCAR-T platform across key unit operations and build up representative small-scale model.

Skills & Requirements

Must-have

  • UCAR-T platform development
  • process parameter optimization
  • PAT and statistical modeling
  • closed and automated systems
  • tech transfer to clinical manufacturing

Nice-to-have

  • IND or BLA experience
  • UCAR-T full scale process platform
  • cross-function collaboration

Key Requirements

  • PhD or MSc in relevant scientific field
  • 2+ years (PhD) or 5+ years (MSc) experience
  • Hands-on CAR-T process development experience
  • Familiarity with UCAR-T gene editing tools
  • Proficiency in JMP statistical software

Work Rights

Not specified

Tailored Resume

Cover Letter