Principal Scientist – Computational Biology & Translational Ai (oncology Precision Medicine)

Amgen

Multiple Locations
Base: 182,535.00 usd - 211,139.00 usd; bonus/equit...
On-site
Generative ai and agentic ai systems
Multi-modal data integration
Pan-asset forward and reverse translation
Amgen is seeking a Principal Scientist in Computational Biology and Translational AI focused on oncology precision medicine. The ideal candidate will have expertise in AI systems and translational science, with responsibilities including the integration of multi-modal data to drive insights and support clinical development

Job Summary

  • This role focuses on pan-asset forward and reverse translation, designing and deploying AI‑enabled analytical and agentic systems that connect preclinical, translational, and clinical data to drive mechanistic understanding, biomarker hypotheses, and development strategy across oncology programs.
  • Lead pan-asset forward and reverse translational analyses, integrating preclinical, translational, and clinical data to generate mechanistic insight, biomarker hypotheses, and development‑relevant evidence.
  • Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities.

Matching Summary

Match Score: 85

Amgen is seeking a Principal Scientist in Computational Biology and Translational AI focused on oncology precision medicine. The ideal candidate will have expertise in AI systems and translational science, with responsibilities including the integration of multi-modal data to drive insights and support clinical development.

Salary

Base: 182,535.00 USD - 211,139.00 USD; Bonus/Equity: discretionary annual bonus program, stock-based long-term incentives; Benefits: comprehensive employee benefits package, Retirement and Savings Plan, group medical, dental and vision coverage, life and disability insurance, flexible spending accounts

Skills & Requirements

Must-have

  • Generative AI and Agentic AI systems
  • multi-modal data integration
  • pan-asset forward and reverse translation
  • clinical biomarker development
  • translational science expertise

Nice-to-have

  • scientific leadership
  • collaborative environment
  • patient-focused mission

Key Requirements

  • Doctorate degree and 2 years of computational Biology experience
  • Master’s degree and 5 years of computational Biology experience
  • Bachelor’s degree and 7 years of computational Biology experience
  • PhD in Bioinformatics, Mathematics, Statistics, Computer Science, Computational Biology, Data Science, or related field
  • Demonstrated expertise in forward and/or reverse translational science
  • Hands-on experience developing Generative AI and/or Agentic AI systems
  • Experience integrating multi-modal data
  • Strong programming experience in R and/or Python

Work Rights

Not specified

Tailored Resume

Cover Letter