Expert Toxicologist For Impurity Safety Assessment And Risk Management

Roche

Basel, Switzerland
Not specified (assumed onsite given the location)
Expertise in ich m7 genotoxic impurities
Experience with e&l toxicological risk assessments
Proficiency in qsar and computational toxicology
Roche is seeking an Expert Toxicologist for Impurity Safety Assessment and Risk Management, based in Basel, Switzerland. The position requires a strong scientific background in toxicology, specifically in impurity assessments, to support the safety evaluation of drug candidates throughout their development

Job Summary

  • This role serves as the single point of contact for impurity and extractables/leachables risk assessments within Roche's Translational Safety Assessment chapter.
  • The position requires conducting comprehensive risk assessments of genotoxic impurities in line with ICH M7 guidance and designing in silico analyses.
  • Roche fosters a culture of curiosity, responsibility, and humility where talented people are empowered to bring forward extraordinary life-changing innovation.

Matching Summary

Match Score: 85

Roche is seeking an Expert Toxicologist for Impurity Safety Assessment and Risk Management, based in Basel, Switzerland. The position requires a strong scientific background in toxicology, specifically in impurity assessments, to support the safety evaluation of drug candidates throughout their development.

Skills & Requirements

Must-have

  • Expertise in ICH M7 genotoxic impurities
  • Experience with E&L toxicological risk assessments
  • Proficiency in QSAR and computational toxicology
  • Knowledge of TTC principles and regulatory guidelines
  • Ability to draft scientifically justified TBLs

Nice-to-have

  • Strong cross-functional collaboration skills
  • Experience representing Roche as KOL
  • Background in drug development processes
  • Commitment to scientific excellence

Key Requirements

  • PhD and MSc in Toxicology or related discipline
  • 5-10 years experience in pharmaceutical toxicology
  • Robust experience in QSARs and impurity safety databases

Work Rights

Not specified

Tailored Resume

Cover Letter