Director, Clinical Pharmacology

Revolution Medicines

Remote
Base: $201,000—$251,000 usd; bonus/equity: not spe...
Remote
Clinical pharmacology strategy
Pk/pd modeling
Ind, eop1 & eop2 briefing documents
Revolution Medicines is seeking a Director of Clinical Pharmacology to join their remote team, focusing on the development of targeted therapies for RAS-addicted cancers. The role requires significant experience in clinical pharmacology within oncology, providing strategic insights and leading technical efforts in drug development

Job Summary

  • Provide strategic insight and technical leadership within the Clinical Pharmacology function.
  • Apply state-of-the-art quantitative modeling, including translational PK/PD, population PK, and exposure-response analyses, to guide recommended phase 2 dose/schedule (RP2Ds) selection for pivotal studies.
  • Represent the Clinical Pharmacology function in project teams and build strong working relationships with cross-functional teams to impact critical decisions.

Matching Summary

Match Score: 85

Revolution Medicines is seeking a Director of Clinical Pharmacology to join their remote team, focusing on the development of targeted therapies for RAS-addicted cancers. The role requires significant experience in clinical pharmacology within oncology, providing strategic insights and leading technical efforts in drug development.

Salary

Base: $201,000—$251,000 USD; Bonus/Equity: Not specified; Benefits: Not specified

Skills & Requirements

Must-have

  • Clinical Pharmacology strategy
  • PK/PD modeling
  • IND, EOP1 & EOP2 Briefing Documents
  • FIH study design
  • hADME, Food-Effect and DDI studies
  • CRO engagement
  • small molecule oncology drug development

Nice-to-have

  • FDA dose optimization interaction
  • PBPK modeling experience

Key Requirements

  • Ph.D. or Pharm.D (with Fellowship)
  • 8+ years of relevant industry experience
  • Prior management experience
  • Familiar with FDA’s Project Optimus guidance
  • Strong understanding of DMPK, CMC and Toxicology

Work Rights

Not specified

Tailored Resume

Cover Letter