Principal Scientist, Chemical Biology - Discovery Chemistry

J&J FAMILY OF COMPANIES

Spring House, Pennsylvania, United States of America
Base: $117,000.00 - $201,250.00; bonus/equity: ann...
**
Organic synthesis
Chemical biology expertise
Design and synthesis of chemical probes
** Johnson & Johnson is seeking a Principal Scientist in Chemical Biology for their Discovery Chemistry team, located in various locations, including Spring House, PA, La Jolla, CA, Beerse, Belgium, and Toledo, Spain. The ideal candidate will possess a PhD in a relevant field and a strong background in chemical biology, with a focus on synthesizing tools for drug discovery. **

Job Summary

  • Drive and direct chemical biology functions for drug discovery projects, working in concert with partners in medicinal chemistry, chemoproteomics, disease area biology, and other key functions.
  • Independently design and synthesize chemical biology tools—including photoaffinity and photocatalytic proximity labeling probes—toward various applications, as well as supervise and direct synthetic chemistry activities at contract research organizations (CROs).
  • The expected base pay range for this position is $117,000 to $201,250.

Matching Summary

Match Score: 75

** Johnson & Johnson is seeking a Principal Scientist in Chemical Biology for their Discovery Chemistry team, located in various locations, including Spring House, PA, La Jolla, CA, Beerse, Belgium, and Toledo, Spain. The ideal candidate will possess a PhD in a relevant field and a strong background in chemical biology, with a focus on synthesizing tools for drug discovery. **

Salary

Base: $117,000.00 - $201,250.00; Bonus/Equity: Annual performance bonus; Benefits: Medical, dental, vision, life insurance, disability, retirement plan, savings plan, vacation, sick time, holiday pay, work/personal/family time, parental leave, condolence leave, caregiver leave, volunteer leave, military spouse time-off

Skills & Requirements

Must-have

  • organic synthesis
  • chemical biology expertise
  • design and synthesis of chemical probes
  • photoaffinity labeling probes
  • activity-based protein profiling
  • target identification
  • target engagement in cells

Nice-to-have

  • biopharmaceutical industry experience
  • targeted protein degradation strategies
  • scientific contributions
  • publication record
  • presentation at conferences

Key Requirements

  • PhD in Organic Chemistry, Medicinal Chemistry, or Chemical Biology
  • 5+ years post-PhD experience in Chemical Biology
  • Structure-Activity Relationship (SAR)-driven design and synthesis
  • chemical biology and chemoproteomics methods
  • demonstrated application of chemical biology
  • succeed within a matrix environment

Work Rights

Not specified

Tailored Resume

Cover Letter