This role serves as the DMPK subject matter expert across Brii’s portfolio, supporting programs from early discovery through clinical development and regulatory submission
Job Summary
This role serves as the DMPK subject matter expert across Brii’s portfolio, supporting programs from early discovery through clinical development and regulatory submission.
Responsible for communication and management of outsourced CROs, as well as overseeing bioanalytical method development and validation to ensure data accuracy and reliability, study quality, timelines, and compliance.
Collaborate cross-functionally with pharmacology, toxicology, CMC, and clinical teams, providing DMPK expertise.
Matching Summary
This role serves as the DMPK subject matter expert across Brii’s portfolio, supporting programs from early discovery through clinical development and regulatory submission.
Skills & Requirements
Must-have
DMPK subject matter expert
in vitro and in vivo ADME studies
PK, metabolism, and exposure assessment
CRO management
bioanalytical method development
Nice-to-have
nucleic acid therapeutics experience
delivery systems familiarity
PBPK modeling and simulation
quantitative pharmacology analysis
Key Requirements
1-3 years of relevant DMPK experience
Bachelor's degree or above in Pharmacy, Pharmacology, Drug Metabolism, Pharmacokinetics, or related field