Director, Safety Science

Generate:Biomedicines

Somerville, MA, United States
On-site
Pharmacovigilance (pv) team
Safety data signal management
Pv organization and process development
Provide strategic scientific and operational PV support for clinical development products, including those transitioning from early to late-phase development

Job Summary

  • Provide strategic scientific and operational PV support for clinical development products, including those transitioning from early to late-phase development.
  • Partner closely with Clinical, Regulatory, Medical, Biostats, and external partners to ensure proactive signal detection and safety risk management in alignment with global regulatory expectations.
  • Help shape the growth of the safety function, including evaluating tools, technologies, and vendors to support future scalability and contributing to team hiring, mentoring, and onboarding.

Matching Summary

Provide strategic scientific and operational PV support for clinical development products, including those transitioning from early to late-phase development.

Skills & Requirements

Must-have

  • Pharmacovigilance (PV) team
  • Safety data signal management
  • PV organization and process development
  • Aggregate data review and signal detection
  • Individual case safety report assessments
  • Reference Safety Information (RSI) development
  • Global safety regulations and ICH guidelines

Nice-to-have

  • Dynamic, fast-paced environment
  • Proactive signal detection and risk management
  • Inspection readiness and vendor management
  • Mentoring and team development
  • Player-coach approach

Key Requirements

  • Advanced clinical degree (MD, DO, or equivalent)
  • Minimum 8 years of experience in drug safety/pharmacovigilance
  • At least 4+ years in safety science roles in clinical development
  • Experience in biotech or small-to-mid-size pharma environment
  • Experience with safety databases (e.g., Argus, VeevaSafety)
  • Experience with MedDRA coding, Points to Consider, AoSE and SMQs
  • Prior involvement in NDA/BLA/MAA submissions or regulatory agency interactions preferred

Work Rights

Not specified

Tailored Resume

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