Sr. Systems Engineer

10x Genomics

Pleasanton, United States
Base: $168,900—$228,500 usd; bonus/equity: eligibl...
On-site
Develop instrument architectures
Conceive and run system-level models
Design & implement custom hardware systems
10x Genomics is seeking a Sr. Systems Engineer to participate in the full product development cycle, focusing on instrument architecture, system modeling, and cross-functional collaboration. Ideal candidates will have a strong background in hardware design and integration, along with proficiency in Python and data analysis

Job Summary

  • As a System Engineer at 10x, you will be involved in all aspects of the product development process, from the initial ideation and requirements generation to prototyping to launch.
  • You will work closely with hardware engineers including mechanical, electrical, optical and fluidic groups and collaborate cross-functionally with software, chemistry and computational biology teams.
  • Ideal candidates will be highly motivated, independent, systems thinkers who value creative and robust design, enjoy working at the seams of different engineering and science disciplines, and have strong data analysis and presentation skills.

Matching Summary

Match Score: 85

10x Genomics is seeking a Sr. Systems Engineer to participate in the full product development cycle, focusing on instrument architecture, system modeling, and cross-functional collaboration. Ideal candidates will have a strong background in hardware design and integration, along with proficiency in Python and data analysis.

Salary

Base: $168,900—$228,500 USD; Bonus/Equity: Eligible for equity grants and annual bonus program; Benefits: Comprehensive health and retirement benefit programs

Skills & Requirements

Must-have

  • Develop instrument architectures
  • Conceive and run system-level models
  • Design & implement custom hardware systems
  • Metrology and testing approaches
  • Cross-functional collaboration
  • Data-driven decisions
  • System-level tests
  • Risk assessments (e.g., FMEAs)

Nice-to-have

  • Holistic, multidisciplinary platform architectures
  • Creative and robust design
  • Working at the seams of disciplines
  • Strong data analysis and presentation skills
  • Experience with standards such as UL 61010-1
  • Design of experiment and statistical analysis
  • Debugging and extending hardware control software

Key Requirements

  • Bachelors in an engineering discipline
  • 5+ years working with hardware systems or instruments
  • Direct experience in a cross-functional role
  • Experience in system modeling for performance/cost tradeoffs
  • Proficiency in Python
  • Comfort implementing in silico models
  • Fluency with modern AI tools

Work Rights

Not specified

Tailored Resume

Cover Letter