Principal Investigator Ii, Bioinformatics

Brii Biosciences

Durham, North Carolina, United States
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Oligonucleotides-based therapeutics
Ai-based machine learning models
Ngs/wgs/gwas/twas/dbsnp/genbank/biobank data
** Brii Biosciences is seeking a Principal Investigator II in Bioinformatics to join their drug discovery team in Durham, North Carolina. The role requires expertise in bioinformatics and oligonucleotide-based therapeutics, with a focus on conducting analyses to support drug development projects while collaborating with a multidisciplinary team. **

Job Summary

  • This role will play a critical role in genetic characterization and design of oligonucleotides-based therapeutics.
  • The successful candidate will conduct bioinformatics analysis or studies to support all phases of exploratory and discovery projects and be required to work creatively and independently on a variety of computational methodologies and AI-based machine learning models.
  • The individual will have strong background in scientific research and organize, analyze and interpret results, come forward with recommendations and present the findings to senior personnel or in team meetings.

Matching Summary

Match Score: 75

** Brii Biosciences is seeking a Principal Investigator II in Bioinformatics to join their drug discovery team in Durham, North Carolina. The role requires expertise in bioinformatics and oligonucleotide-based therapeutics, with a focus on conducting analyses to support drug development projects while collaborating with a multidisciplinary team. **

Skills & Requirements

Must-have

  • oligonucleotides-based therapeutics
  • AI-based machine learning models
  • NGS/WGS/GWAS/TWAS/dbSNP/GenBank/BioBank data
  • bioinformatics analytical platform management
  • electronic lab notebook systems

Nice-to-have

  • target biology and MoA exploration
  • sequence designation and alignment
  • human genetic variants identification
  • off-target prediction and evaluation
  • pathway analysis and network analysis

Key Requirements

  • PhD or equivalent with 8+ years of post-degree experience
  • Demonstrated track record of scientific industry research or publications
  • Hands-on bioinformatics experience in oligonucleotides-based drug discovery
  • Strong written, verbal, and interpersonal communications skills

Work Rights

Not specified

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