Senior Scientist Ii/associate Principal Scientist, Pharmacology

AstraZeneca

Shanghai, China
Humanized mouse in vivo studies
Car-t pharmacology expertise
Flow cytometry panel design
You will lead in vivo pharmacology and immune monitoring to enable data-driven progression of programs from discovery toward translation with a priority focus on cell therapy (CAR-T), immuno-oncology, and immunology

Job Summary

  • You will lead in vivo pharmacology and immune monitoring to enable data-driven progression of programs from discovery toward translation with a priority focus on cell therapy (CAR-T), immuno-oncology, and immunology.
  • The role involves ownership of humanized mouse platforms and associated workflows delivering rigorous datasets that inform candidate selection, dose strategy, mechanism understanding, and biomarker hypotheses.
  • You will drive alignment with multiple internal teams, present results and recommendations in cross-functional forums, and contribute to best-practice standardization and mentoring.

Matching Summary

You will lead in vivo pharmacology and immune monitoring to enable data-driven progression of programs from discovery toward translation with a priority focus on cell therapy (CAR-T), immuno-oncology, and immunology.

Skills & Requirements

Must-have

  • Humanized mouse in vivo studies
  • CAR-T pharmacology expertise
  • Flow cytometry panel design
  • Study leadership and vendor management
  • In vivo oncology and immunology modeling
  • Data analysis and visualization tools
  • Immune monitoring and functional characterization

Nice-to-have

  • Immune profiling integration
  • Translational biomarker strategy
  • Immuno-oncology combination strategies
  • Cross-functional team collaboration
  • Mentoring within in vivo community

Key Requirements

  • PhD or MD with translational research experience
  • Demonstrated small animal in vivo expertise
  • Practical humanized mouse study experience
  • Strong CAR-T biology knowledge
  • Hands-on flow cytometry competence
  • Proven study leadership skills
  • Proficiency with ELN and analysis tools
  • Strong English communication skills

Work Rights

Not specified

Tailored Resume

Cover Letter