AstraZeneca’s Cell Therapy R&D is dedicated to discovering, engineering, and developing next generation cellular therapies to address high unmet medical needs across the clinical portfolio
Job Summary
AstraZeneca’s Cell Therapy R&D is dedicated to discovering, engineering, and developing next generation cellular therapies to address high unmet medical needs across the clinical portfolio.
The role involves leading innovative cell therapy science for engineered CAR-T products targeting solid and hematologic tumors, integrating process development and CMC considerations.
The position requires collaboration with internal and external partners to drive technology transfer, scale-up, and clinical supply while ensuring compliance with AstraZeneca policies and applicable laws.
Matching Summary
AstraZeneca’s Cell Therapy R&D is dedicated to discovering, engineering, and developing next generation cellular therapies to address high unmet medical needs across the clinical portfolio.
Skills & Requirements
Must-have
Cell therapy process development and CMC
LVV upstream and downstream process development
Cell based assay establishment and validation
Gene editing and CAR-T engineering
Cross-functional project execution
Virus analytical method qualification
Compliance with GxP and manufacturing regulations
Nice-to-have
Independent project initiation and execution
Strong interpersonal and collaboration skills
Proficient English communication and writing
Knowledge of regulatory frameworks for cell/gene therapies
Understanding of CQAs/CPPs and DoE process characterization
Key Requirements
Masters or PhD in Cell/Molecular Biology or related field
Demonstrable experience in cell therapy PD and CMC
Hands-on experience with LVV process development and CAR-T manufacturing
Proven track record in analytical method validation for cell therapy
Experience collaborating with CDMOs and external suppliers
Knowledge of GxP and laboratory/manufacturing regulations