Director/associate Director - R&d Discovery Vector Engineering

AstraZeneca

Mont-Saint-Guibert, Belgium
**
Phd in molecular biology or related field
8+ years gene therapy r&d experience
Lentiviral vector (lvv) engineering expertise
** AstraZeneca is seeking a Director/Associate Director for R&D Discovery Vector Engineering at their Mont-Saint-Guibert, Belgium location. The role involves leading the discovery and engineering of novel lentiviral vectors, collaborating across various teams, and ensuring high-quality outcomes in gene therapy research. **

Job Summary

  • This role involves leading the discovery and engineering of novel lentiviral vectors from concept through preclinical candidate selection to eliminate barriers in traditional cell therapies.
  • The successful candidate will build scalable screening platforms and integrate developability and CMC considerations early to ensure scalability, yield, purity, and stability.
  • As a proud new member of the AstraZeneca group, Esobiotec offers a dynamic environment where scientific passion drives real-world impact on life-changing treatments.

Matching Summary

Match Score: 75

** AstraZeneca is seeking a Director/Associate Director for R&D Discovery Vector Engineering at their Mont-Saint-Guibert, Belgium location. The role involves leading the discovery and engineering of novel lentiviral vectors, collaborating across various teams, and ensuring high-quality outcomes in gene therapy research. **

Skills & Requirements

Must-have

  • PhD in molecular biology or related field
  • 8+ years gene therapy R&D experience
  • Lentiviral vector (LVV) engineering expertise
  • Experience with viral vector design and optimization
  • CMC collaboration and process development partnership
  • Leadership of small-to-medium discovery teams
  • IP strategy and FTO analysis proficiency

Nice-to-have

  • AAV or related viral system knowledge
  • Statistical design and high-throughput screening
  • Cross-functional product-focused approach
  • External collaboration and CRO management
  • Culture of scientific excellence and urgency

Key Requirements

  • PhD in molecular biology, virology, or bioengineering
  • 12+ years experience for Director level
  • 8+ years experience for Associate Director level
  • Demonstrated success in viral vector engineering
  • Proven track record in IP and patent drafting

Work Rights

Not specified

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