Senior Principal Scientist – Chemical Biology & Proximity-based Therapeutics

Amgen Inc

Base: $162,509.80 - $219,866.20 usd annually; bonu...
Not specified
Doctorate degree in chemical biology or related field
3 years experience in chemical biology and small molecule discovery
Experience with proximity-based mechanisms or molecular glues
Amgen Inc is seeking a Senior Principal Scientist in Chemical Biology & Proximity-based Therapeutics to lead innovative research efforts in drug discovery, particularly focusing on molecular glue discovery and induced proximity mechanisms. The ideal candidate will have extensive experience in chemical biology and small molecule discovery, along with a strong collaborative spirit to thrive in a dynamic team environment

Job Summary

  • This role leads discovery efforts at the intersection of chemical biology, induced proximity, and phenotypic drug discovery to address previously undruggable targets.
  • The successful candidate will design and implement phenotypic screening strategies to uncover novel therapeutic opportunities for serious illnesses.
  • Amgen offers a comprehensive benefits package including retirement plans, health coverage, stock-based incentives, and flexible work models.

Matching Summary

Match Score: 85

Amgen Inc is seeking a Senior Principal Scientist in Chemical Biology & Proximity-based Therapeutics to lead innovative research efforts in drug discovery, particularly focusing on molecular glue discovery and induced proximity mechanisms. The ideal candidate will have extensive experience in chemical biology and small molecule discovery, along with a strong collaborative spirit to thrive in a dynamic team environment.

Salary

Base: $162,509.80 - $219,866.20 USD annually; Bonus/Equity: Discretionary annual bonus and stock-based long-term incentives; Benefits: Comprehensive health, dental, vision, retirement plan, and flexible time-off

Skills & Requirements

Must-have

  • Doctorate degree in Chemical Biology or related field
  • 3 years experience in chemical biology and small molecule discovery
  • Experience with proximity-based mechanisms or molecular glues

Nice-to-have

  • Demonstrated experience developing phenotypic screening assays
  • Strong background in mechanism-of-action studies
  • Track record of scientific publications and patents
  • Familiarity with proteomics and transcriptomics approaches

Key Requirements

  • Doctorate degree required
  • Minimum 3 years relevant experience
  • Experience with molecular glue discovery

Work Rights

Not specified

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