Senior Scientist - Process Analytical Technology - Apicom
AstraZeneca
Dublin, , Ireland
Process analytical technology (pat) leadership
Cgmp manufacturing environment
Chemometric model development
AstraZeneca is a global, innovation-driven biopharmaceutical company committed to delivering life-saving medicines with a culture that inspires innovation and collaboration
Job Summary
AstraZeneca is a global, innovation-driven biopharmaceutical company committed to delivering life-saving medicines with a culture that inspires innovation and collaboration.
The role involves leading the introduction and implementation of PAT instruments and methods in a state-of-the-art API Commercialisation Facility in Dublin, collaborating across multidisciplinary teams.
The company offers an inclusive culture that champions diversity, lifelong learning, and provides reasonable accommodations for individuals with disabilities.
Matching Summary
AstraZeneca is a global, innovation-driven biopharmaceutical company committed to delivering life-saving medicines with a culture that inspires innovation and collaboration.
Skills & Requirements
Must-have
Process Analytical Technology (PAT) leadership
cGMP manufacturing environment
Chemometric model development
Near-IR, mid-IR, Raman spectroscopy
Pharmaceutical drug substance manufacturing
PAT instrument operation and maintenance
Nice-to-have
Siemens SIPAT superuser experience
Technical supervision and mentoring
Change management in regulated environment
Development and transfer of multivariate models
MATLAB or Python coding skills
Training and coaching colleagues
Key Requirements
Bachelor’s or PhD in chemistry, analytical chemistry, or chemical engineering
Experience in R&D and/or manufacturing environment
Proven record in drug substance control strategies using PAT
Significant practical experience with major PAT spectroscopic techniques
Strong data-centric mindset with chemometrics expertise
Understanding of SHE and cGMP principles for drug substance manufacturing