Principal Scientist, Process Chemistry

Calicolabs

South San Francisco, CA, United States
Base: $198,000 - $241,000; bonus/equity: two annua...
On-site (5 days a week)
Process research and scale-up
Organic molecule synthesis
Synthetic process optimization
Calico Life Sciences is seeking a Principal Scientist in Process Chemistry to join their lab-based chemical development team in South San Francisco. The role requires extensive experience in organic chemistry, focusing on the development and optimization of synthetic processes for drug manufacturing

Job Summary

  • Calico is seeking an experienced Process Chemist to join our laboratory-based chemical development team.
  • In this role, you will design, optimize, and execute synthetic processes that enable efficient, safe, and scalable manufacturing of small-molecule intermediates and APIs.
  • This is a lab-focused position requiring strong experimental skills, deep organic chemistry knowledge, and the ability to translate laboratory findings into robust processes.

Matching Summary

Match Score: 85

Calico Life Sciences is seeking a Principal Scientist in Process Chemistry to join their lab-based chemical development team in South San Francisco. The role requires extensive experience in organic chemistry, focusing on the development and optimization of synthetic processes for drug manufacturing.

Salary

Base: $198,000 - $241,000; Bonus/Equity: two annual cash bonuses; Benefits: Not specified

Skills & Requirements

Must-have

  • process research and scale-up
  • organic molecule synthesis
  • synthetic process optimization
  • analytical techniques (HPLC, GC, LC-MS)
  • impurity identification and synthesis
  • technology transfer to CMOs

Nice-to-have

  • curiosity-driven discovery science
  • inspiring and exciting place
  • proactive, collaborative mindset
  • enthusiasm for process improvement

Key Requirements

  • PhD in Organic Chemistry or related field
  • 8+ years of relevant industrial experience
  • Familiarity with cGMP and ICH guidelines

Work Rights

Not specified

Tailored Resume

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