(senior) Principal Scientist, Extracellular Targeted Cancer Therapeutics

GlaxoSmithKline

Hybrid
Extracellular targeted cancer therapeutics
Antibody-drug conjugates (adcs)
T cell engagers (tces)
GlaxoSmithKline is seeking a (Senior) Principal Scientist for its Extracellular Targeted Cancer Therapeutics unit, focusing on pre-clinical and early clinical phases of biologics, particularly antibody-drug conjugates and T cell engagers. The ideal candidate should possess extensive experience in cancer biology, leadership in drug discovery, and a solid background in relevant laboratory techniques

Job Summary

  • The Extracellular Targeted Cancer Therapeutics (ETCT) Biology Unit within the Oncology Research Unit is seeking an experienced Principal Scientist/Senior Principal Scientist to contribute to programs in pre-clinical and early clinical phases in the targeted biologics portfolio focusing on antibody-drug conjugates (ADCs) and T cell engagers (TCEs).
  • The candidate will work within multi-disciplinary program teams by contributing to and leading biology strategy, delivering molecule mechanism of action and potency data and providing input into other functions such as pharmacokinetics, non-clinical safety, biomarkers and clinical development.
  • We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

Matching Summary

Match Score: 85

GlaxoSmithKline is seeking a (Senior) Principal Scientist for its Extracellular Targeted Cancer Therapeutics unit, focusing on pre-clinical and early clinical phases of biologics, particularly antibody-drug conjugates and T cell engagers. The ideal candidate should possess extensive experience in cancer biology, leadership in drug discovery, and a solid background in relevant laboratory techniques.

Skills & Requirements

Must-have

  • Extracellular Targeted Cancer Therapeutics
  • antibody-drug conjugates (ADCs)
  • T cell engagers (TCEs)
  • pre-clinical and early clinical phases
  • mechanism of action and potency data
  • design and execute impactful experiments

Nice-to-have

  • agile working culture
  • collaborative team environment
  • champion innovative experimental techniques
  • build communication networks

Key Requirements

  • BSc. or higher degree in Cell Biology, Pharmacology, Immunology or related fields
  • significant pharmaceutical or biotechnology industry research and leadership experience
  • Experience in progressing cancer therapies from target ID to candidate selection
  • Experience leading cross-functional drug discovery project teams
  • Demonstrated technical expertise in cell culture, cell-based assays, immunoassays, Flow Cytometry

Work Rights

Not specified

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