Principal Scientist, Protein Therapeutics – Mammalian Expression & Cell Line Engineering

Amgen Inc

Base: $140,123.35 - $189,578.65 usd; bonus/equity:...
Phd or master's degree with relevant experience
Mammalian cell biology expertise
Cell line engineering strategies
This senior individual contributor role provides scientific leadership to drive innovation in mammalian expression systems and cell line engineering for large-molecule therapeutics

Job Summary

  • This senior individual contributor role provides scientific leadership to drive innovation in mammalian expression systems and cell line engineering for large-molecule therapeutics.
  • The successful candidate will solve complex problems related to recombinant protein expression, post-translational modification, and developability while partnering with informatics teams.
  • Amgen offers a comprehensive benefits package including retirement plans, health coverage, stock-based incentives, and flexible work models to support professional growth.

Matching Summary

This senior individual contributor role provides scientific leadership to drive innovation in mammalian expression systems and cell line engineering for large-molecule therapeutics.

Salary

Base: $140,123.35 - $189,578.65 USD; Bonus/Equity: Discretionary annual bonus and stock-based long-term incentives; Benefits: Comprehensive health, dental, vision, retirement plan, and flexible time-off

Skills & Requirements

Must-have

  • PhD or Master's degree with relevant experience
  • Mammalian cell biology expertise
  • Cell line engineering strategies
  • High-throughput expression workflows
  • Data-driven decision making

Nice-to-have

  • Automation-enabled workflow implementation
  • Strong publication and patent record
  • Cross-functional collaboration skills
  • Influence without authority
  • External scientific forum participation

Key Requirements

  • Doctorate (PhD/MD) with 2 years cell biology OR Master's with 5 years OR Bachelor's with 7 years
  • Deep expertise in mammalian expression and construct design
  • Proven independent scientific achievement via publications or patents

Work Rights

Not specified

Tailored Resume

Cover Letter