Director Of Clinical Pharmacology And Quantitative Medicine
GSK
Pennsylvania, United States
Hybrid
Pharmacokinetic and pharmacodynamic models
Model-informed drug development
Clinical pharmacology studies
Lead development and application of pharmacokinetic, pharmacodynamic and mechanistic models to inform dose selection, trial design and evidence generation
Job Summary
Lead development and application of pharmacokinetic, pharmacodynamic and mechanistic models to inform dose selection, trial design and evidence generation.
Collaborate with clinical, translational, biomarker, regulatory and statistical teams to design efficient clinical development plans.
Communicate results clearly to diverse audiences through reports, presentations and scientific publications.
Matching Summary
Lead development and application of pharmacokinetic, pharmacodynamic and mechanistic models to inform dose selection, trial design and evidence generation.
Skills & Requirements
Must-have
pharmacokinetic and pharmacodynamic models
model-informed drug development
clinical pharmacology studies
quantitative input for regulatory interactions
cross-functional team collaboration
Nice-to-have
scientific curiosity and clear communication
ambitious for patients
data science approaches
mentoring junior scientists
Key Requirements
PhD, PharmD or equivalent degree
Minimum 5 years industry experience
Hands-on experience with pharmacometrics tools
Experience contributing to regulatory submissions
Ability to design and interpret clinical pharmacology studies