Senior Scientist Ii, Cell Therapy Discovery

AstraZeneca

Phd in immunology or cell biology
Human primary cell culture expertise
Lentiviral vector preparation and transduction
You will own key assays and workflows for CAR design, T-cell engineering, and in vitro functional characterization

Job Summary

  • You will own key assays and workflows for CAR design, T-cell engineering, and in vitro functional characterization.
  • The role requires designing constructs, characterizing engineered cell therapies, and developing optimized functional assays.
  • You will partner with cross-functional teams including Pharmacology, CMC, and clinical groups to advance project milestones.

Matching Summary

You will own key assays and workflows for CAR design, T-cell engineering, and in vitro functional characterization.

Skills & Requirements

Must-have

  • PhD in immunology or cell biology
  • Human primary cell culture expertise
  • Lentiviral vector preparation and transduction
  • Flow cytometry panel design and analysis
  • Functional assays for target killing
  • Molecular methods including PCR and NGS

Nice-to-have

  • Experience with armored or logic gated CARs
  • Program advancement from lead to preclinical
  • Method transfer and qualification support
  • Mentoring colleagues in lab environment
  • Troubleshooting complex experimental models

Key Requirements

  • PhD in immunology, cell biology, or related field
  • MS with 4+ years demonstrated impact in cell therapy discovery
  • Proficiency with ELN, FlowJo, Snapgene, and GraphPad

Work Rights

Not specified

Tailored Resume

Cover Letter