Research Fellow - Vascular Biology, Human Genetics, And Fibromuscular Dysplasia (fmd)
Mass General Brigham
Boston, Massachusetts, United States
Hybrid
Phd in human genetics or vascular biology
Experience with gwas and whole-exome sequencing
Crispr/cas9 genome editing expertise
The position involves joining an international, multidisciplinary research program focused on defining the mechanisms underlying fibromuscular dysplasia
Job Summary
The position involves joining an international, multidisciplinary research program focused on defining the mechanisms underlying fibromuscular dysplasia.
The fellow will analyze human genetic data and integrate findings with cellular and in vivo functional studies to identify therapeutic targets.
Candidates must have a strong background in molecular biology and demonstrate the ability to translate genetic findings into testable biological hypotheses.
Matching Summary
The position involves joining an international, multidisciplinary research program focused on defining the mechanisms underlying fibromuscular dysplasia.
Skills & Requirements
Must-have
PhD in human genetics or vascular biology
Experience with GWAS and whole-exome sequencing
CRISPR/Cas9 genome editing expertise
Vascular smooth muscle cell culture experience
Murine model of cardiovascular disease
Nice-to-have
Integration of multi-omics datasets
Familiarity with statistical genetics pipelines
Experience with extracellular matrix biology
Interest in sex-specific genetic effects
Collaborative data analysis environment skills
Key Requirements
PhD or MD/PhD required
Demonstrated experience in human genetics analysis
Hands-on experience with CRISPR/Cas9 or iPSC culture
Strong record of peer-reviewed publication potential