Scientist To Senior Scientist, Process Development

Brii Biosciences

Shanghai, Shanghai, China
On-site
Oligonucleotide cmc process development
Enzymatic ligation optimization
Gmp manufacturing collaboration
Brii Biosciences is seeking a Scientist to Senior Scientist for their Process Development team in Shanghai, focusing on oligonucleotide pipeline drugs. The role involves developing and optimizing processes for oligonucleotide synthesis and purification, requiring collaboration with internal teams and external CDMOs

Job Summary

  • The Scientist will develop, analyze, and optimize processes for manufacturing oligonucleotides with novel chemistry and functionality.
  • This role requires close collaboration with early discovery teams to transition novel chemistry into CMC IND-enabling processes.
  • The successful candidate must maintain comprehensive documentation in the Company Electronic Laboratory Notebook while working independently and within a team.

Matching Summary

Match Score: 85

Brii Biosciences is seeking a Scientist to Senior Scientist for their Process Development team in Shanghai, focusing on oligonucleotide pipeline drugs. The role involves developing and optimizing processes for oligonucleotide synthesis and purification, requiring collaboration with internal teams and external CDMOs.

Skills & Requirements

Must-have

  • Oligonucleotide CMC process development
  • Enzymatic ligation optimization
  • GMP manufacturing collaboration
  • Electronic Laboratory Notebook documentation
  • CDMO oversight and troubleshooting

Nice-to-have

  • Novel chemical structure expertise
  • Fast-paced multi-tasking environment
  • Strong internal collaboration culture
  • Intellectual property building experience

Key Requirements

  • Minimum B.S. in Chemistry or related field
  • 3 years of pharmaceutical or biotech industry experience
  • Hands-on oligonucleotide drug substance process development
  • Experience with enzymatic ligation is desirable

Work Rights

Not specified

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