Principal Scientist, Primary Pharmacology

Pfizer

Groton, CT, USA
Base: $106,000.00 to $176,600.00; bonus/equity: 15...
Onsite
12 years experience or phd with 4 years
Expertise in multiple in vitro assay formats
Experience with immortalized and primary cells
The role involves joining the Discovery Biology and Pharmacology group to accelerate hit identification and lead optimization for small molecule drug discovery

Job Summary

  • The role involves joining the Discovery Biology and Pharmacology group to accelerate hit identification and lead optimization for small molecule drug discovery.
  • Candidates will independently design and perform in vitro assays using biochemical and cellular systems to drive SAR and mechanistic pharmacology.
  • The position offers a competitive base salary ranging from $106,000.00 to $176,600.00 along with a 15% bonus target and comprehensive benefits.

Matching Summary

The role involves joining the Discovery Biology and Pharmacology group to accelerate hit identification and lead optimization for small molecule drug discovery.

Salary

Base: $106,000.00 to $176,600.00; Bonus/Equity: 15.0% target bonus plus share based long term incentive; Benefits: 401(k) matching, paid vacation, health/dental/vision coverage

Skills & Requirements

Must-have

  • 12 years experience or PhD with 4 years
  • Expertise in multiple in vitro assay formats
  • Experience with immortalized and primary cells
  • Molecular biology techniques RT-qPCR transfection western blotting
  • Laboratory automation and data analysis systems

Nice-to-have

  • Experience mentoring junior colleagues
  • Knowledge of metabolic and cardiovascular disease concepts
  • Strong bases in protein pathway studies
  • Experience with multiple target classes like GPCRs
  • Collaborative cross-disciplinary partnership building

Key Requirements

  • BA/BS with 12 years or MS with 9 years or PhD with 4 years relevant experience
  • Demonstrated expertise with HTRF ELISA FP BRET assay formats
  • Practical experience with molecular biology techniques including RT-qPCR and western blotting
  • Permanent work authorization in the United States required

Work Rights

Must have permanent work authorization in the U.S.

Tailored Resume

Cover Letter