Job Summary

• The candidates will develop, optimize and apply cutting-edge cellular/ molecular methods to generate 3D in vitro and ex vivo tumor models that adequately recapitulate the tumor architecture and mimic the cell-to-cell interactions within the tissue microenvironment.
• Main responsibilities include processing patient-derived samples according to pre-established guidelines (e.g., tissue dissociation, isolation of PBMCs/ TILs, endothelial cells, sample freezing and storage, nucleic acids and protein extraction, and patient-derived tumor organoid/ fragment generation and maintenance) generation and maintenance of cell cultures and execution of experiments on cell cultures updating the database of patient samples and reagents documenting the experiments providing general support for lab maintenance within the scope of this project.
• These positions offer exciting opportunities for highly motivated individuals to contribute to advancing personalized medicine in cancer.

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Skills & Requirements

Key Requirements

• Laboratory Technician degree or Bachelor/Master degree
• experience handling and processing patient samples
• experience with cell culture and flow cytometry
• experience in primary cell culture and 3D cultures
• experience in organoid generation and maintenance

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