Senior Scientist I, Cell Therapy Discovery

Tryzenoya

Human t-cell isolation and culture
Lentiviral transduction and electroporation
Flow cytometry panel design and analysis
You will own key assays and workflows for CAR design, T-cell engineering, and in vitro functional characterization

Job Summary

  • You will own key assays and workflows for CAR design, T-cell engineering, and in vitro functional characterization.
  • You will work with project teams to make data-driven decisions to move programs from discovery toward translation.
  • You will also help shape study plans, align internal and external teams, and ensure timely delivery of milestones across functions.

Matching Summary

You will own key assays and workflows for CAR design, T-cell engineering, and in vitro functional characterization.

Skills & Requirements

Must-have

  • Human T-cell isolation and culture
  • Lentiviral transduction and electroporation
  • Flow cytometry panel design and analysis
  • Functional assays for cell killing and proliferation
  • Molecular methods including PCR/qPCR
  • Proficiency with ELN, FlowJo, GraphPad

Nice-to-have

  • Experience with armored CARs or logic-gated CARs
  • Familiarity with AML disease
  • Advancing CAR-T candidates through lead optimization
  • Method transfer and qualification
  • Scale-up evaluations for gene-modified T-cell products

Key Requirements

  • PhD in immunology, cell biology, or related field
  • MS with 2-3+ years demonstrated impact in cell therapy discovery
  • Biosafety level 2 practices
  • Research GxP awareness

Work Rights

Not specified

Tailored Resume

Cover Letter