Principal Or Senior Principal Scientist Computational Drug Discovery

Zealand Pharma AS

Cambridge, Massachusetts, United States
Base: $220,000 - $270,000; bonus/equity: not speci...
Not specified
Phd in computational chemistry or related field
6+ years post-degree experience in computational drug discovery
Deep expertise in structure-guided modeling
Zealand Pharma AS is seeking a Principal or Senior Principal Scientist for Computational Drug Discovery in Cambridge, Massachusetts. The ideal candidate will have extensive experience in computational drug discovery, particularly in peptide and protein-based modalities, and will play a key role in shaping research strategies and fostering collaboration within the organization

Job Summary

  • The role serves as a senior individual contributor and scientific leader influencing discovery direction across multiple programs within Zealand Pharma's new Molecular Platform Development unit.
  • Candidates will define computational strategies aligned with the metabolic disease portfolio and co-develop hypotheses to accelerate iterative design-make-test-analyze cycles.
  • Zealand Pharma offers a unique culture characterized by excellent teamwork, curiosity, and playfulness, aiming to advance medicines for obesity and metabolic health.

Matching Summary

Match Score: 85

Zealand Pharma AS is seeking a Principal or Senior Principal Scientist for Computational Drug Discovery in Cambridge, Massachusetts. The ideal candidate will have extensive experience in computational drug discovery, particularly in peptide and protein-based modalities, and will play a key role in shaping research strategies and fostering collaboration within the organization.

Salary

Base: $220,000 - $270,000; Bonus/Equity: Not specified; Benefits: Not specified

Skills & Requirements

Must-have

  • PhD in Computational Chemistry or related field
  • 6+ years post-degree experience in computational drug discovery
  • Deep expertise in structure-guided modeling
  • Experience with protein and peptide-based drug discovery
  • Track record of advancing molecules to clinical development

Nice-to-have

  • Postdoctoral training preferred
  • Collaborative mindset with experimental teams
  • Integration of LLM-based methods
  • Strong cross-functional understanding of early development

Key Requirements

  • PhD required in Computational Chemistry, Biology, Biochemistry, Structural Biology, or Chemical Biology
  • 6+ years relevant experience for Principal Scientist; 8+ years for Senior Principal Scientist
  • Demonstrated track record of computational insights influencing clinical development
  • Not specified

Work Rights

Not specified

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