Senior Scientist I, Bioanalysis And Translational Medicine
AstraZeneca
Master's degree in molecular biology or related field
5+ years experience in molecular testing
Pcr-based analytical method development and validation
The role focuses on data-driven bioanalysis and translational research to support cell therapy programs including CAR-T and mRNA-LNP/lentiviral in vivo CAR
Job Summary
The role focuses on data-driven bioanalysis and translational research to support cell therapy programs including CAR-T and mRNA-LNP/lentiviral in vivo CAR.
Responsibilities include defining standards for sample collection, performing DNA/RNA extraction, and conducting qPCR/ddPCR assays for biomarkers like VCN and RCL.
The position requires ensuring compliance with AstraZeneca policies, GCP regulations, and effectively managing relationships with external testing partners.
Matching Summary
The role focuses on data-driven bioanalysis and translational research to support cell therapy programs including CAR-T and mRNA-LNP/lentiviral in vivo CAR.
Skills & Requirements
Must-have
Master's degree in molecular biology or related field
5+ years experience in molecular testing
PCR-based analytical method development and validation
Experience with qPCR and ddPCR assays
Knowledge of Good Clinical Practice (GCP) regulations
Nice-to-have
Understanding of drug and companion diagnostic co-development
Experience with NGS, IHC, and ISH/FISH techniques
Strong interpersonal skills for cross-functional collaboration
Ability to work independently under tight timelines
Experience managing external CRO alliances
Key Requirements
Master's degree or above in molecular biology, genomics, or immunology
At least 5 years of experience in clinical laboratory work
Proven track record in developing PCR-based methods for clinical samples