Hybrid (minimum of three days in-office per week with flexible arrangements)
Oncology expertise required
Pkpd modeling and dmpk science
Antibody drug conjugates (adcs) experience
AstraZeneca is seeking a Senior Scientist in Translational PKPD for their Cambridge, UK location, focusing on DMPK science as it relates to oncology. The ideal candidate will possess expertise in pharmacokinetics and pharmacodynamics modeling, with a strong background in DMPK and experience in cross-functional collaboration within pharmaceutical R&D
Job Summary
The role involves driving strategy and providing global leadership in DMPK science for Antibody Drug Conjugates and Radioconjugates.
Candidates will explore PK/PD/Efficacy relationships in pre-clinical models to build a quantitative understanding of dose and schedule requirements.
The company fosters an inclusive environment where unexpected teams collaborate to inspire life-changing medicines through bold thinking.
Matching Summary
Match Score: 85
AstraZeneca is seeking a Senior Scientist in Translational PKPD for their Cambridge, UK location, focusing on DMPK science as it relates to oncology. The ideal candidate will possess expertise in pharmacokinetics and pharmacodynamics modeling, with a strong background in DMPK and experience in cross-functional collaboration within pharmaceutical R&D.
Skills & Requirements
Must-have
Oncology expertise required
PKPD modeling and DMPK science
Antibody Drug Conjugates (ADCs) experience
WinNonLin/Phoenix NLME proficiency
R programming language skills
SimCYP and NonMem tools
Berkeley Madonna and MATLAB
Nice-to-have
Strong publication record in DMPK
Cross-functional collaboration skills
Strategic scientific initiative leadership
Global influence in clinical pharmacology
Experience with Radioconjugates (RCs)
Key Requirements
University Degree in pharmaceutical sciences or quantitative field
Relevant industry experience in DMPK/preclinical roles
Track record of supporting PK, PKPD, and TKPD projects