Drug Metabolism Identification Scientist

Roche

Lc-hrms instrumentation operation
Phase i/ii biotransformation pathways
In vitro metabolite profiling studies
The role involves conducting in vitro and in vivo metabolite identification studies across various species to support drug development

Job Summary

  • The role involves conducting in vitro and in vivo metabolite identification studies across various species to support drug development.
  • Candidates will operate advanced LC-HRMS instrumentation and interpret complex fragmentation patterns to propose accurate chemical structures.
  • Roche fosters a culture of personal expression and open dialogue where every voice matters in the mission to prevent and cure diseases.

Matching Summary

The role involves conducting in vitro and in vivo metabolite identification studies across various species to support drug development.

Skills & Requirements

Must-have

  • LC-HRMS instrumentation operation
  • Phase I/II biotransformation pathways
  • In vitro metabolite profiling studies
  • Structural elucidation via MS/MS
  • Glutathione trapping assays

Nice-to-have

  • Antibody-Drug Conjugate MetID experience
  • Cross-functional collaboration skills
  • Distilling complex data for stakeholders
  • CRO partnership management

Key Requirements

  • Ph.D. in Analytical Chemistry or Biochemistry with 4+ years experience
  • MS degree with 8+ years dedicated industry experience
  • Mastery of liquid chromatography and high-resolution mass spectrometry

Work Rights

Not specified

Tailored Resume

Cover Letter