Job Summary

• The Principal Scientist, ADPKD Biology Lead is a senior, lab-embedded scientific leader responsible for shaping and executing ADPKD discovery biology strategy across a portfolio of preclinical programs.
• The role will translate insights from human genetics and disease biology into differentiated target hypotheses, lead target triage and validation in advanced human-relevant model systems, including 3D platforms, and deliver decision-grade biology packages to enable robust, biology-driven portfolio go/no-go decisions and progression to preclinical proof-of-concept.
• US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits.

Matching Summary

Salary

Base: $108,500 - $201,500 for Principal Scientist I, $126,000 - $234,000 for Principal Scientist II; Bonus/Equity: performance-based cash incentive and eligibility for annual equity awards; Benefits: comprehensive health, life, disability, 401(k) with company match, generous time off

Skills & Requirements

Key Requirements

• PhD in relevant biological sciences
• 8–10+ years kidney disease research
• drug discovery experience in pharma/biotech
• deep expertise in renal cystogenesis pathophysiology
• experience with target identification and validation
• excellent English communication skills

Work Rights