Principal Scientist, Primary Pharmacology

Pfizer

Groton, CT, United States
Base: $106,000.00 to $176,600.00; bonus/equity: 15...
Onsite
In vitro assay development and troubleshooting
Biochemical and cellular system experience
Immortalized and primary cell handling
The role involves joining the Discovery Biology and Pharmacology group to accelerate hit identification and lead optimization for small molecule drug discovery

Job Summary

  • The role involves joining the Discovery Biology and Pharmacology group to accelerate hit identification and lead optimization for small molecule drug discovery.
  • Candidates must independently design and perform in vitro assays using biochemical and cellular systems to drive SAR and mechanistic pharmacology.
  • The position offers a competitive base salary ranging from $106,000.00 to $176,600.00 with a 15% bonus target and comprehensive benefits.

Matching Summary

The role involves joining the Discovery Biology and Pharmacology group to accelerate hit identification and lead optimization for small molecule drug discovery.

Salary

Base: $106,000.00 to $176,600.00; Bonus/Equity: 15% target bonus plus share based long term incentive; Benefits: 401(k) matching, paid vacation, health coverage

Skills & Requirements

Must-have

  • in vitro assay development and troubleshooting
  • biochemical and cellular system experience
  • immortalized and primary cell handling
  • molecular biology techniques including RT-qPCR
  • laboratory automation and data analysis systems

Nice-to-have

  • experience mentoring junior colleagues
  • knowledge of metabolic and cardiovascular disease concepts
  • strong bases in protein and pathway studies
  • collaborative cross-disciplinary partnership building

Key Requirements

  • BA/BS with 12 years or MS with 9 years or PhD with 4 years relevant experience
  • Demonstrated expertise with multiple in vitro assay formats like HTRF, ELISA, FP, BRET
  • Practical experience with molecular biology techniques such as transfection and western blotting
  • Must have permanent work authorization in the United States

Work Rights

Must have permanent work authorization in the United States

Tailored Resume

Cover Letter