Senior Principal Scientist, Biopharmaceutics

Johnson & Johnson

Malvern, Pennsylvania, United States
Hybrid
Biologics biopharmaceutics development
Subcutaneous (sc) delivery platforms
Pharmacokinetic (pk) modeling
This role will lead scientific strategies and experimental programs to enable subcutaneous (SC) delivery platforms, bridging strategies, combination product development, and targeted delivery approaches

Job Summary

  • This role will lead scientific strategies and experimental programs to enable subcutaneous (SC) delivery platforms, bridging strategies, combination product development, and targeted delivery approaches.
  • Apply expertise in pharmacokinetics, biopharmaceutics, and formulation science to advance biologics from early development through clinical phases.
  • Represent Biopharmaceutics on Chemistry, Manufacturing and Controls (CMC) and development teams and mentor junior scientists.

Matching Summary

This role will lead scientific strategies and experimental programs to enable subcutaneous (SC) delivery platforms, bridging strategies, combination product development, and targeted delivery approaches.

Skills & Requirements

Must-have

  • Biologics biopharmaceutics development
  • Subcutaneous (SC) delivery platforms
  • Pharmacokinetic (PK) modeling
  • Bridging strategies (IV-to-SC, SC-to-SC)
  • Combination product development
  • Targeted delivery approaches

Nice-to-have

  • Innovative non-aqueous suspension formulations
  • In vitro and in silico tools
  • Model-informed approaches
  • Creative scientific mindset
  • Collaborate effectively with cross-functional teams

Key Requirements

  • Ph.D. in Pharmaceutical Sciences or related discipline
  • 6+ years of experience in biologics development
  • Experience in pharmacokinetic modeling
  • Experience with bridging strategies
  • Proficiency in PK modeling tools (Phoenix WinNonlin, Simcyp, etc.)
  • Deep understanding of ADME of therapeutic proteins

Work Rights

Not specified

Tailored Resume

Cover Letter