Principal Scientist - Clinical Pharmacology, Modeling & Simulation

Amgen

Base: $162,988.00 - $192,921.00 usd annually; bonu...
Hybrid
Doctorate degree with experience
Pk/pd modeling expertise
M-pbpk modeling skills
The role drives innovative modeling and simulation strategies to support clinical dosage selections and study designs across oncology, rare diseases, obesity, and cardiovascular disease

Job Summary

  • The role drives innovative modeling and simulation strategies to support clinical dosage selections and study designs across oncology, rare diseases, obesity, and cardiovascular disease.
  • Candidates must apply quantitative translational and clinical pharmacology approaches including PK/PD, M-PBPK, and QSP modeling integrated with emerging Machine Learning and Generative AI.
  • Amgen offers a comprehensive benefits package including retirement plans, health coverage, stock-based incentives, and flexible work arrangements.

Matching Summary

The role drives innovative modeling and simulation strategies to support clinical dosage selections and study designs across oncology, rare diseases, obesity, and cardiovascular disease.

Salary

Base: $162,988.00 - $192,921.00 USD annually; Bonus/Equity: Discretionary annual bonus and stock-based long-term incentives; Benefits: Comprehensive health, dental, vision, retirement plan, and flexible time-off

Skills & Requirements

Must-have

  • Doctorate degree with experience
  • PK/PD modeling expertise
  • M-PBPK modeling skills
  • QSP modeling knowledge
  • Model Based Drug Development track record

Nice-to-have

  • Machine Learning and Generative AI integration
  • Global health authority interaction experience
  • Collaborative and innovative culture fit
  • Leadership in clinical study design

Key Requirements

  • PhD or Master's/Bachelor's with specific years of experience
  • 5+ years in Clinical Pharmacology and Modeling & Simulation
  • Expert knowledge of PK/PD and M-PBPK software
  • Track record of regulatory document authoring

Work Rights

Not specified

Tailored Resume

Cover Letter