Senior Principal Ai/ml Cheminformatics Scientist

Pfizer

Base: $124,400.00 to $207,400.00; bonus/equity: 17...
Hybrid
Ai/ml model development for drug discovery
Python proficiency with rdkit and deepchem
Experience with qsar and generative models
Pfizer is seeking a Senior Principal AI/ML Cheminformatics Scientist to drive advancements in drug discovery using AI and cheminformatics. The ideal candidate will have extensive experience in drug discovery, expertise in AI methodologies, and strong collaboration skills to work with cross-functional teams

Job Summary

  • The role involves designing and deploying innovative cheminformatics and AI workflows to prioritize compound lists and optimize lead strategies.
  • Candidates must have a Ph.D. or Master's degree plus 8+ years of experience applying AI methods to medicinal chemistry challenges.
  • The position offers a base salary range of $124,400 to $207,400 with a 17.5% bonus target and comprehensive benefits including 401(k) matching.

Matching Summary

Match Score: 85

Pfizer is seeking a Senior Principal AI/ML Cheminformatics Scientist to drive advancements in drug discovery using AI and cheminformatics. The ideal candidate will have extensive experience in drug discovery, expertise in AI methodologies, and strong collaboration skills to work with cross-functional teams.

Salary

Base: $124,400.00 to $207,400.00; Bonus/Equity: 17.5% target bonus plus share-based long term incentive; Benefits: 401(k) matching, paid vacation, medical/dental/vision coverage

Skills & Requirements

Must-have

  • AI/ML model development for drug discovery
  • Python proficiency with RDKit and DeepChem
  • Experience with QSAR and generative models
  • Molecular representations and chemical fingerprints
  • Virtual screening and ADMET modeling expertise

Nice-to-have

  • Leadership experience coaching others
  • Ability to influence cross-functional teams
  • Track record of co-authored publications
  • Proactive adoption of emerging methodologies
  • Strategic technology adoption capabilities

Key Requirements

  • Ph.D. or Master's degree in Cheminformatics or related field
  • 8+ years of drug discovery industry experience
  • Strong Python skills with cheminformatics libraries
  • Permanent work authorization in the United States required
  • No visa sponsorship available for this role

Work Rights

Must have permanent work authorization in the US

Tailored Resume

Cover Letter