Senior Scientist Ii, Cell Therapy Discovery

AstraZeneca

Shanghai, China
Primary human cell culture and activation
Lentiviral vector preparation and transduction
Flow cytometry panel design and gating
You will own key assays and workflows for CAR design, T-cell engineering, and in vitro functional characterization to advance programs from discovery toward translation

Job Summary

  • You will own key assays and workflows for CAR design, T-cell engineering, and in vitro functional characterization to advance programs from discovery toward translation.
  • The role involves designing and running studies, analyzing data, preparing reports, and collaborating with multiple scientific teams to ensure timely delivery of milestones.
  • AstraZeneca embraces diversity and equality of opportunity and is committed to building an inclusive and diverse team representing all backgrounds.

Matching Summary

You will own key assays and workflows for CAR design, T-cell engineering, and in vitro functional characterization to advance programs from discovery toward translation.

Skills & Requirements

Must-have

  • Primary human cell culture and activation
  • Lentiviral vector preparation and transduction
  • Flow cytometry panel design and gating
  • Functional assays for target killing and cytokines
  • Molecular methods including PCR and NGS prep
  • Compliance with BSL 2 biosafety and animal ethics

Nice-to-have

  • Cross-functional project collaboration
  • Scientific writing and presentation skills
  • Mentoring and lab team leadership
  • Troubleshooting and protocol optimization
  • Experience with armored and logic gated CARs

Key Requirements

  • PhD in immunology, cell biology, or related field or MS with 4+ years impact
  • Experience in cell therapy discovery
  • Adherence to biosafety and animal ethics regulations

Work Rights

Not specified

Tailored Resume

Cover Letter