Senior Scientist, Cellular Lead Profiling (automation)

Takeda

Boston, MA, US
Base: $137,000.00 - $215,270.00; bonus/equity: sho...
High content assay development and execution
Automated liquid handling systems operation
Statistical analysis of assay performance metrics
The Senior Scientist will drive the design and execution of robust cellular assays on fully automated, integrated platforms to support Takeda's Lab of the Future initiative

Job Summary

  • The Senior Scientist will drive the design and execution of robust cellular assays on fully automated, integrated platforms to support Takeda's Lab of the Future initiative.
  • This role requires applying advanced statistical methodologies to ensure high-quality, reproducible data generation for iterative AI-integrated Design–Make–Test–Analyze cycles.
  • Candidates must possess a Ph.D. in Cell Biology or related fields with significant industry experience in developing high-content assays for small- and large-molecule discovery.

Matching Summary

The Senior Scientist will drive the design and execution of robust cellular assays on fully automated, integrated platforms to support Takeda's Lab of the Future initiative.

Salary

Base: $137,000.00 - $215,270.00; Bonus/Equity: Short-term and/or long-term incentives eligible; Benefits: Medical, dental, vision, 401(k) match, up to 120 hours vacation

Skills & Requirements

Must-have

  • High Content Assay development and execution
  • Automated liquid handling systems operation
  • Statistical analysis of assay performance metrics
  • 384-well and 1536-well plate format miniaturization
  • GPCR and ion channel screening expertise
  • Integration with LIMS/ELN data pipelines

Nice-to-have

  • Experience with AI/ML in DMTA processes
  • Cross-functional collaboration skills
  • Mentoring junior scientific staff
  • Knowledge of acoustic dispensing technologies
  • Background in oncology or gastrointestinal diseases

Key Requirements

  • Ph.D. in Cell Biology, Pharmacology, or related discipline
  • 2+ years of industry experience (or M.S./B.S. with more)
  • Hands-on experience with GPCR and ion channel assays
  • Proficiency in operating robotic liquid handlers like Echo or Hamilton
  • Strong background in statistical analysis (Z', CV, S/B)

Work Rights

Not specified

Tailored Resume

Cover Letter