Senior Scientist Protein Science & Engineering Large Molecule Biologics

Lilly

South San Francisco, CA, USA
$151,500 - $222,200; bonus: compyny bonus; benefit...
Hybrid
Lc/ms characterization of adcs
Mass spectrometry bioanalysis
Protein chemistry
The Bioanalytical Research Group (BAR) at Lilly’s research facility in South San Francisco, CA is seeking a strong scientist skilled in protein mass spectrometry to deliver innovative ways in our evaluation of the ADME properties of therapeutic proteins and antibody-drug-conjugates (ADCs)

Job Summary

  • The Bioanalytical Research Group (BAR) at Lilly’s research facility in South San Francisco, CA is seeking a strong scientist skilled in protein mass spectrometry to deliver innovative ways in our evaluation of the ADME properties of therapeutic proteins and antibody-drug-conjugates (ADCs).
  • Primary Responsibilities include the development and application of QQQ and high-resolution LC/MS approaches to characterize the PK, biotransformation, and biodistribution of ADC drug candidates in pre-clinical animal models.
  • Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance).

Matching Summary

The Bioanalytical Research Group (BAR) at Lilly’s research facility in South San Francisco, CA is seeking a strong scientist skilled in protein mass spectrometry to deliver innovative ways in our evaluation of the ADME properties of therapeutic proteins and antibody-drug-conjugates (ADCs).

Salary

$151,500 - $222,200; Bonus: Company bonus; Benefits: Comprehensive benefit program

Skills & Requirements

Must-have

  • LC/MS characterization of ADCs
  • mass spectrometry bioanalysis
  • protein chemistry
  • Sciex 7500 operation
  • Thermo Orbitrap operation
  • sample preparation techniques

Nice-to-have

  • MS-informatic approaches
  • automation experience
  • high throughput assays
  • proteomics methods
  • cell culture experience
  • R or python experience

Key Requirements

  • Ph.D. in biochemistry/molecular biology or related field
  • Experience with mass spectrometry bioanalysis of ADCs
  • Experience with method development and troubleshooting mass spectrometers
  • Experience with sample preparation techniques including SPE
  • Experience with ADC drug development programs

Work Rights

Not specified

Tailored Resume

Cover Letter