Associate Principal Scientist – Purification Scientist

Merck & Co., Inc.

Base: $142,400.00 - $224,100.00; bonus/equity: ann...
Hybrid
Hplc/uplc method development
Protein a affinity capture chromatography
Ion exchange (cex/aex) chromatography
The role involves developing innovative separation, analysis, and characterization strategies to accelerate the development of new medicines and vaccines

Job Summary

  • The role involves developing innovative separation, analysis, and characterization strategies to accelerate the development of new medicines and vaccines.
  • Candidates will partner with bioprocess and analytical scientists to deploy efficient bio/chemical isolation methods and deliver high purity materials.
  • The position offers a comprehensive benefits package including medical, dental, vision, 401(k), and eligibility for annual bonuses and long-term incentives.

Matching Summary

The role involves developing innovative separation, analysis, and characterization strategies to accelerate the development of new medicines and vaccines.

Salary

Base: $142,400.00 - $224,100.00; Bonus/Equity: Annual bonus and long-term incentive eligible; Benefits: Medical, dental, vision, 401(k), paid holidays, vacation

Skills & Requirements

Must-have

  • HPLC/UPLC method development
  • Protein A affinity capture chromatography
  • Ion exchange (CEX/AEX) chromatography
  • Size exclusion (SEC) chromatography
  • Hydrophobic interaction (HIC) chromatography
  • Reversed-phase chromatography
  • Drug-to-antibody ratio (DAR) analysis

Nice-to-have

  • Multidimensional separation techniques (2DLC)
  • SEC-MALS and DLS biophysical characterization
  • Peptide mapping and glycan profiling
  • Intact and subunit LC-MS structural workflows
  • Deep appreciation of chemical structure interplay

Key Requirements

  • Ph.D. in biochemistry/chemistry with 3-5 years experience
  • M.S. with minimum 8 years experience in biopharmaceutical industry
  • Hands-on experience with mAbs and ADC purification
  • Experience with sample preparation minimizing adsorption/degradation

Work Rights

Not specified

Tailored Resume

Cover Letter