Principal Scientist, Biology-discovery

539

Rahway, NJ, USA
Base: $173,200.00 - $272,600.00; bonus/equity: ann...
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Deep expertise in quantitative pharmacology
Strong mathematical fluency in calculus and odes
Experience with dose-response and enzyme kinetics
** The Principal Scientist position in Biology-discovery at Merck in Rahway, NJ, seeks an expert in quantitative pharmacology and biochemistry to enhance drug discovery efforts. The role involves developing and applying quantitative models to guide drug development, mentoring junior scientists, and fostering collaboration across research teams. **

Job Summary

  • The role provides senior-level expertise at the interface of in vitro pharmacology and quantitative modeling to guide drug discovery decisions.
  • Candidates will develop and apply mechanistic models to characterize compound activity and translate pharmacological data into actionable recommendations for medicinal chemistry.
  • The position offers a competitive salary range of $173,200.00 - $272,600.00 along with comprehensive benefits including medical, dental, vision, and 401(k) retirement plans.

Matching Summary

Match Score: 75

** The Principal Scientist position in Biology-discovery at Merck in Rahway, NJ, seeks an expert in quantitative pharmacology and biochemistry to enhance drug discovery efforts. The role involves developing and applying quantitative models to guide drug development, mentoring junior scientists, and fostering collaboration across research teams. **

Salary

Base: $173,200.00 - $272,600.00; Bonus/Equity: Annual bonus and long-term incentive eligible; Benefits: Medical, dental, vision, 401(k), paid holidays, vacation

Skills & Requirements

Must-have

  • Deep expertise in quantitative pharmacology
  • Strong mathematical fluency in calculus and ODEs
  • Experience with dose-response and enzyme kinetics
  • Ability to develop mechanistic data models
  • PhD in pharmacology or biochemistry required

Nice-to-have

  • Proficiency in Python or R for scientific computing
  • Familiarity with DNA-encoded libraries and HTS
  • Experience with high-content imaging and transcriptomics
  • Strong mentorship and cross-functional collaboration skills
  • Knowledge of mass spectrometry and proteomics

Key Requirements

  • Ph.D. in pharmacology, biochemistry, biophysics, or related discipline
  • 10 years of relevant drug discovery experience
  • Demonstrated impact across multiple programs and therapeutic areas
  • VISA Sponsorship available for eligible candidates

Work Rights

Not specified

Sponsorship: available

Tailored Resume

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