Senior Scientist - Sirna Off-target Analysis

Amgen UK

Base: $129,228.90 - $174,839.10 usd; bonus: discre...
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Phd or master's with 3 years experience
Python and r programming expertise
Bulk rna-seq data analysis skills
** Amgen UK is seeking a Senior Scientist specializing in siRNA off-target analysis. The ideal candidate will possess expertise in computational biology and transcriptomics, contributing to the assessment of off-target effects in drug development while supporting a culture centered around patient care. **

Job Summary

  • This role applies expertise in transcriptomics and computational biology to design off-target assessments for siRNA experiments.
  • The successful candidate will develop scalable analysis pipelines using Python and R while ensuring FAIR data practices.
  • Amgen offers a comprehensive benefits package including retirement plans, health coverage, and flexible work models.

Matching Summary

Match Score: 75

** Amgen UK is seeking a Senior Scientist specializing in siRNA off-target analysis. The ideal candidate will possess expertise in computational biology and transcriptomics, contributing to the assessment of off-target effects in drug development while supporting a culture centered around patient care. **

Salary

Base: $129,228.90 - $174,839.10 USD; Bonus: Discretionary annual bonus program; Benefits: Comprehensive health, dental, vision, retirement plan, stock incentives

Skills & Requirements

Must-have

  • PhD or Master's with 3 years experience
  • Python and R programming expertise
  • Bulk RNA-seq data analysis skills
  • Transcriptomics and proteomics interpretation
  • FAIR data principles implementation

Nice-to-have

  • Single-cell RNA-seq analysis experience
  • AI-enabled workflow development
  • LLM-assisted analytical tools usage
  • Nonclinical safety data familiarity
  • Regulatory document drafting experience

Key Requirements

  • Doctorate degree (PhD/MD) OR Master's with 3 years experience
  • Strong background in computational biology and bioinformatics
  • Experience with nonclinical safety data and toxicology
  • Ability to draft regulatory documents and reports

Work Rights

Not specified

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