Senior Principal Investigator, Bioinformatics

Brii Biosciences

Shanghai, Shanghai, China
On-site
Ngs/wgs/gwas/twas/dbsnp/genbank/biobank data analysis
Oligonucleotides-based bioinformatics
Design and execute bioinformatics studies
The individual will play a critical role in genetic characterization and design of oligonucleotides-based therapeutics

Job Summary

  • The individual will play a critical role in genetic characterization and design of oligonucleotides-based therapeutics.
  • The successful candidate will conduct bioinformatics analysis or studies to support all phases of exploratory and discovery projects and be required to work creatively and independently on a variety of computational methodologies and AI-based machine learning models.
  • Primary responsibilities will be oligonucleotides-based bioinformatics activities to design and execute bioinformatics studies, generate data and report results to a broad program team.

Matching Summary

The individual will play a critical role in genetic characterization and design of oligonucleotides-based therapeutics.

Skills & Requirements

Must-have

  • NGS/WGS/GWAS/TWAS/dbSNP/GenBank/BioBank data analysis
  • Oligonucleotides-based bioinformatics
  • Design and execute bioinformatics studies
  • Data structuring, management, analysis, visualization
  • Computational methodologies and AI/ML models

Nice-to-have

  • Target biology and MoA exploration
  • Sequence designation and alignment
  • Human genetic variants identification
  • Off-target prediction and evaluation
  • Pathway analysis and network analysis

Key Requirements

  • PhD or equivalent with 10+ years post-degree experience
  • Industry experience preferred
  • Hands-on bioinformatics experience in oligonucleotides-based drug discovery
  • Strong written, verbal, and interpersonal communication skills

Work Rights

Not specified

Tailored Resume

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