Senior Principal Scientist, Long-acting Sterile Product Development

Merck & Co., Inc.

Rahway, NJ, USA
Base: $190,800.00 - $300,300.00; bonus/equity: ann...
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Ph.d. in pharmaceutics or related field
8+ years industry experience in parenteral development
Expertise in long-acting injectable formulation science
** Merck & Co., Inc. is seeking a Senior Principal Scientist for Long-acting Sterile Product Development in Rahway, NJ. The role involves leading technical strategies for developing parenteral dosage forms, particularly long-acting injectables, while collaborating with cross-functional teams to ensure product quality and compliance. **

Job Summary

  • This role serves as a senior principal-level scientific leader responsible for the design and lifecycle management of long-acting injectable drug products from preclinical development through commercialization.
  • The successful candidate will lead cross-functional teams to define critical quality attributes, optimize release kinetics, and ensure manufacturability for sterile parenteral dosage forms.
  • Candidates are eligible for an annual bonus, long-term incentives, and a comprehensive benefits package including medical, dental, vision, and 401(k) retirement plans.

Matching Summary

Match Score: 75

** Merck & Co., Inc. is seeking a Senior Principal Scientist for Long-acting Sterile Product Development in Rahway, NJ. The role involves leading technical strategies for developing parenteral dosage forms, particularly long-acting injectables, while collaborating with cross-functional teams to ensure product quality and compliance. **

Salary

Base: $190,800.00 - $300,300.00; Bonus/Equity: Annual bonus and long-term incentive available; Benefits: Medical, dental, vision, 401(k), paid holidays, vacation

Skills & Requirements

Must-have

  • Ph.D. in Pharmaceutics or related field
  • 8+ years industry experience in parenteral development
  • Expertise in long-acting injectable formulation science
  • Experience with controlled-release mechanisms and polymers
  • Knowledge of Quality by Design (QbD) principles
  • Proven track record in process scale-up and validation

Nice-to-have

  • Experience with device-drug product integration
  • Background in clinical strategy and risk mitigation
  • Contributions to publications or patents in drug delivery
  • Understanding of patient-centric LAI design considerations
  • Experience supporting global regulatory filings

Key Requirements

  • Ph.D. with 8+ years experience or M.S. with 10+ years
  • Deep expertise in parenteral drug product development
  • Strong understanding of drug-polymer interactions
  • Experience with CMC regulatory expectations
  • Demonstrated ability to lead cross-functional teams

Work Rights

Not specified

Sponsorship: available

Tailored Resume

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