Lead CAR construct design and engineering, characterizing activity of engineered cell therapies using human primary cells and functional co-culture assays
Job Summary
Lead CAR construct design and engineering, characterizing activity of engineered cell therapies using human primary cells and functional co-culture assays.
Apply a rigorous, data-driven approach to experimental design, mechanism-of-action studies, and decision-making, using appropriate analytics and visualization.
AstraZeneca embraces diversity and equality of opportunity, committed to building an inclusive and diverse team representing all backgrounds.
Matching Summary
Lead CAR construct design and engineering, characterizing activity of engineered cell therapies using human primary cells and functional co-culture assays.
Skills & Requirements
Must-have
CAR construct design and engineering
Human primary cell assays
Flow cytometry panel design
Functional killing assays
Lentiviral transduction optimization
ELN, FlowJo, GraphPad proficiency
Nice-to-have
Armored CARs experience
Allogeneic edits experience
Personalized healthcare enthusiasm
Productive lab environment fostering
Key Requirements
PhD in immunology, cell biology, or related field
MS with 5+ years experience
Work authorization and employment eligibility verification