Senior Research Scientist, Human Cell Engineering And In Vitro Disease Modeling

Vertex Pharmaceuticals

San Diego, CA, United States
Base: $121,600 - $182,400; bonus/equity: eligible ...
On-site
Human cell biology expertise
Ipsc technologies
Gene editing (crispr/cas9)
Develop engineered human cell models for drug discovery workflows to support translational relevance and advance the company's pipeline

Job Summary

  • Develop engineered human cell models for drug discovery workflows to support translational relevance and advance the company's pipeline.
  • Apply expertise in human cell biology, iPSC technologies, and gene editing to create robust in vitro disease models for various drug discovery stages.
  • Collaborate with cross-functional teams to integrate disease models into compound screening, target validation, and mechanistic studies, analyzing and communicating findings.

Matching Summary

Develop engineered human cell models for drug discovery workflows to support translational relevance and advance the company's pipeline.

Salary

Base: $121,600 - $182,400; Bonus/Equity: Eligible for annual bonus and equity awards; Benefits: Market-leading benefits including medical, dental, vision, PTO, educational assistance, 401(k)

Skills & Requirements

Must-have

  • Human cell biology expertise
  • iPSC technologies
  • Gene editing (CRISPR/Cas9)
  • In vitro disease models
  • Compound screening integration

Nice-to-have

  • Scientific curiosity
  • Multidisciplinary team collaboration
  • Emerging technology awareness
  • Continuous improvement methodologies

Key Requirements

  • Ph.D. with 2-5 years post-doc experience OR Masters with 5+ years experience OR Bachelors with 8+ years experience
  • Relevant scientific discipline (Cell Biology, Molecular Biology, Neuroscience, etc.)
  • Experience with iPSC differentiation workflows
  • Proficiency with CRISPR/Cas9 gene editing
  • Hands-on validation methods (RNAseq, qPCR, NGS, Western blot, immunostaining)

Work Rights

Not specified

Tailored Resume

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