Group Leader, Oligonucleotides Chemistry

A*STAR RESEARCH ENTITIES

Singapore
Not specified; competitive compensation pyckage al...
Not specified
Doctorate degree in chemistry or related field
7+ years hands-on nucleoside synthesis experience
Expertise in spos instrumentation and purification systems
A*STAR's Nucleic Acid Therapeutics Initiative (NATi) is seeking a Group Leader for Oligonucleotides Chemistry in Singapore. The role involves overseeing oligonucleotide chemistry capabilities and leading a team in the development of RNA-based therapeutics

Job Summary

  • The role involves overseeing NATi's oligonucleotide chemistry capabilities spanning pre-clinical synthesis, separation, and analytical characterization workflows.
  • Candidates will drive end-to-end oligonucleotide generation to support multiple discovery programs and contribute to pipeline advancement toward drug candidate selection.
  • This position offers a highly competitive compensation package aligned with global industry standards within Singapore's thriving biomedical innovation ecosystem.

Matching Summary

Match Score: 85

A*STAR's Nucleic Acid Therapeutics Initiative (NATi) is seeking a Group Leader for Oligonucleotides Chemistry in Singapore. The role involves overseeing oligonucleotide chemistry capabilities and leading a team in the development of RNA-based therapeutics.

Salary

Not specified; Competitive compensation package aligned with global industry standards; Attractive benefits and long-term career growth opportunities

Skills & Requirements

Must-have

  • Doctorate degree in Chemistry or related field
  • 7+ years hands-on nucleoside synthesis experience
  • Expertise in SPOS instrumentation and purification systems
  • Experience managing research teams and CROs
  • Track record of advancing oligonucleotide therapeutics

Nice-to-have

  • Understanding of cardiovascular and metabolic disorders
  • Experience with non-canonical chemistries and novel constructs
  • Strong mentorship skills for junior scientists
  • Background in IP generation and patent filing
  • Collaboration experience with delivery and analytical teams

Key Requirements

  • Doctorate degree required
  • Minimum 7-13 years of relevant experience
  • Proven track record in therapeutic oligonucleotide discovery

Work Rights

Not specified

Tailored Resume

Cover Letter